Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery
نویسندگان
چکیده
منابع مشابه
Smart polymers for responsive drug-delivery systems.
The rapid advancement of biomedical research has led to many creative applications for biocompatible polymers. As modern medicine discerns more mechanisms, both of physiology and of pathophysiology, the approach to healing is to mimic, or if possible, to recreate the physiology of healthy functioning. Thus, the area of smart polymers for responsive drug delivery has evolved. The developments fa...
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Amphiphilic block copolymer micelles have been the focus of research for the last decades because of the promising properties as nano size drug delivery vehicles. In polar aqueous milieu, copolymers self assemble into micelle structures which consist of hydrophilic corona and hydrophobic core regions. Space created inside the micelle core can be used for transportation of drug molecules of hydr...
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Nanoparticles are being widely explored as potential therapeutics for numerous applications in medicine and have been shown to significantly improve the circulation, biodistribution, efficacy, and safety profiles of multiple classes of drugs. One leading class of nanoparticles involves the use of linear, cyclodextrin-containing polymers (CDPs). As is discussed in this paper, CDPs can incorporat...
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Stimuli-responsive polymers show a sharp change in properties upon a small or modest change in environmental condition, e.g. temperature, light, salt concentration or pH. This behaviour can be utilised for the preparation of so-called 'smart' drug delivery systems, which mimic biological response behaviour to a certain extent. The possible environmental conditions to use for this purpose are li...
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ژورنال
عنوان ژورنال: Nanomaterials
سال: 2021
ISSN: 2079-4991
DOI: 10.3390/nano11010188